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bp0018cpr30 | Control of Prenatal Development | CPR2009

Functional genomic approaches for the study of fetal/placental development in swine with special emphasis on imprinted genes

Bischoff S.R. , Tsai S. , Hardison N. , Motsinger-Reift A.A. , Freking B.A. , Piedrahita J.A.

This chapter describes the application of functional genomic approaches to the study of imprinted genes in swine. While there are varied definitions of "functional genomics", in general they focus on the application of DNA microarrays, single nucleotide polymorphism (SNP) arrays, and other high coverage genomic analyses, and their combination with downstream methods of gene modification such as silencing RNA (siRNA) and viral and non-viral transfection. Between the initi...